Question: Her blood pressure is 148/72 mm Hg. Which of the following medication regimens is most appropriate for secondary prevention of stroke for AV?

Answer Options:
A. Warfarin PO once daily, INR target 2.5-3.5
B. Aspirin/ER dipyridamole PO twice daily
C. Dabigatran PO twice daily
D. Aspirin plus clopidogrel PO once daily

Answer: B – Aspirin/ER dipyridamole PO twice daily

 

Question: Which electrolyte disorder can induce hypocalcemia?

Answer Options:
A. Hypophosphatemia
B. Hypokalemia
C. Hypermagnesemia
D. Hyperphosphatemia
E. Hyperkalemia

Answer: D – Hyperphosphatemia

 

Question: JG is a 70-year-old male with atrial fibrillation, hypertension, and a history of TIAs. What medication regimen is most appropriate for stroke prevention for JG?

Answer Options:
A. Apixaban PO twice daily
B. Aspirin plus clopidogrel PO once daily
C. Aspirin/ER dipyridamole PO twice daily
D. Aspirin PO once daily
E. Warfarin PO once daily, INR range 2.5-3.5

Answer: A – Apixaban PO twice daily

 

Question: LJ is a 56-year-old male who has chronic stable angina which is being managed medically. He currently is stabilized on metoprolol tartrate (Lopressor®) 100 mg PO BID. LJ has decided that he would like to lose weight and become more physically active for his New Year’s resolution. However, LJ is concerned because exercise usually seems to trigger an episode of angina for him. Which medication can LJ take immediately prior to exercising to prevent an episode of angina?

Answer Options:
A. Amlodipine (Norvasc®)
B. Ranolazine (Ranexa®)
C. Nitroglycerin SL (Nitrostat®)
D. Isosorbide mononitrate (Imdur®)

Answer: C – Nitroglycerin SL (Nitrostat®)

 

Question: Which of the following are exclusion criteria for thrombolytic therapy in acute ischemic stroke (AIS)? Select all that apply.

Answer Options:
A. History of intracranial hemorrhage
B. Blood pressure greater than 160/90 mm Hg
C. Last dose of a direct oral anticoagulant (DOAC) less than 72 hours ago
D. Symptom onset > 4.5 hours
E. Active internal bleeding

Answer: A, C, D, E

A – History of intracranial hemorrhage
C – Last dose of a direct oral anticoagulant (DOAC) less than 72 hours ago
D – Symptom onset > 4.5 hours
E – Active internal bleeding

 

Question: Platelet aggregation is promoted by:

Answer Options:
A. Increasing intracellular cAMP levels.
B. Inhibition of P2Y₁₂ receptors.
C. Activation of phosphodiesterase (PDE) enzymes.
D. Activation of protein kinase A.

Answer: C – Activation of phosphodiesterase (PDE) enzymes.

 

Question: Which of the following medications inhibit platelets irreversibly? Select all that apply.

Answer Options:
A. Aspirin
B. Cangrelor (Kengreal®)
C. Clopidogrel (Plavix®)
D. Prasugrel (Effient®)
E. Ticagrelor (Brilinta®)
F. Ibuprofen (Advil®)

Answer: A, C, D

A – Aspirin
C – Clopidogrel (Plavix®)
D – Prasugrel (Effient®)

 

Question: GJ is a 68-year-old male who presents to the doctor’s office with a chief complaint of severe pain, numbness, and tingling in his legs when he walks short distances. GJ has a past history of HTN, dyslipidemia, type 2 diabetes, and a 54 pack-year history of smoking. His current medications include aspirin, candesartan (Atacand®), rosuvastatin (Crestor®), and metformin (Glucophage®). To assess his symptoms, an ankle-brachial index (ABI) was measured with the following result: 0.54 (≤0.90 abnormal). Which of the following is the most appropriate medication to manage GJ’s leg symptoms?

Answer Options:
A. Isosorbide mononitrate (Imdur®)
B. Clopidogrel (Plavix®)
C. Cilostazol (Pletal®)
D. Ranolazine (Ranexa®)

Answer: C – Cilostazol (Pletal®)

 

Question: Which protein converts fibrinogen to fibrin?

Answer Options:
A. Antithrombin
B. Prothrombin
C. Prothrombin activator
D. Thrombin

Answer: D – Thrombin

 

Question: The route of administration of fibrinolytic drugs is:

Answer Options:
A. Intravenous
B. Subcutaneous
C. Intramuscular
D. Oral

Answer: A – Intravenous