Question: What is the HLB value of a surfactant composed of 10 g of Span 80 (HLB 4.3) and 5 g of Tween 20 (HLB 16.7)?
Answer Options:
A) 10.5
B) 21
C) 8.4
D) 1.4
Answer: C) 8.4
Question: The package insert states that if you add 80 mL of water to a dry powder, you create 100 mL of a drug suspension at a concentration of ___ mg/mL. How much water should you add to the dry powder to fill an order for the drug at a final concentration of 120 mg/5mL (i.e., 50 mL suspension)?
Answer Options:
A) 24 mL of water
B) 50 mL of water
C) 30 mL of water
D) 20 mL of water
Answer: A) 24 mL of water
Question: What is the melting temperature of a batch of suppositories comprised of 30 g of PEG 1450 (m.p. 44°C) and 70 g of PEG 8000 (m.p. 60°C)?
Answer Options:
N/A
Answer: 55.2°C
Question: Which of the following is an efficacy monitoring parameter of Lasix in the setting of treating acute kidney injury?
Answer Options:
A) Heart rate
B) SCr
C) Urine sodium
D) Fever
Answer: B) SCr
Question: Round the following to three (3) significant figures: (a) 23.65 (b) 6.12963 (c) 0.04372 (d) 400.6247
Answer Options:
N/A
Answer: (a) 23.7 (b) 6.13 (c) 0.0437
Question: You need to prepare 17 doses of a topiramate medicated powder. Each dose contains 25 mg of topiramate. You have on hand 100-mg topiramate tablets. The tablets are unscored (not scored). Each topiramate tablet weighs 325 mg. Do NOT include extra for losses in these calculations. How many topiramate tablets will you need to crush to fill this prescription? To the nearest mg, what is the total weight of crushed topiramate tablet powder that will be dispensed as the medicated powder? Again, do not include extra. Please include units.
Answer Options:
N/A
Answer: 2 tablets 650 mg
Question: If a bottle of 1250 mg clarithromycin powder is reconstituted with 27 mL of water, a 50-mL suspension of 125 mg clarithromycin/5mL is obtained. Make sure you include units in your answers. How much volume does the powder occupy? If the desired concentration was 100 mg clarithromycin/5mL, what would be the desired final volume of the suspension? How much water would you add to the clarithromycin powder if the desired concentration was 100 mg clarithromycin/5mL?
Answer Options:
N/A
Answer: 23 mL 62.5 mL 40 mL
Question: To prepare a stable emulsion you need at least 4 ingredients. They are a water phase, an oil phase, an emulsifier and ___.
Answer Options:
N/A
Answer: Energy
Question: Aliquot method problem: You may use any approach you desire to answer this problem as long as your aliquot contains the amount of desired drug. A prescription requires 50 mg of drug. The LWQ of your balance is 150 mg. You will use the aliquot method to prepare the formulation. Explain your approach by answering the questions below. Include units. You may simply type the question number and your response for each question (e.g., (1) 10 mg, (2) 20 mg, (3) 30 mg, (4) 40 mg). How much drug do you weigh to make a trituration? How much diluent do you weigh and add to the trituration? What is weight of the aliquot of the trituration (drug + diluent) that you will use for the prescription?
Answer Options:
N/A
Answer: 150 mg drug 150 mg diluent 100 mg aliquot (which contains 50 mg drug)
Question: SJ and WR are picking up identical prescriptions. The prescriptions will be applied topically. SJ is a 25 yo female. WR is a 75 yo female. Which counseling point or question would LEAST appropriate to give to BOTH patients, SJ and WR? Select ONE.
Answer Options:
A) Do you understand the instructions for applying the cream, such as how to apply it, where to apply it and how often?
B) If you are pregnant or might become pregnant, you should let your doctor know because you might pass this medication on to your fetus.
C) Make sure you use the enclosed bandages (dressings) because the application site should be covered after you apply the cream.
Answer: B) If you are pregnant or might become pregnant, you should let your doctor know because you might pass this medication on to your fetus.
Question: Patients on anticoagulants should seek medical attention for bleeding for which of the following situations? Select all that apply
Answer Options:
A) Coughing or vomiting blood or “coffee-grounds”
B) Red or dark brown urine
C) Tarry, black, coffee-ground, or red-colored stools
D) Nose bleed spontaneously, resolving within 60 seconds
Answer: A) Coughing or vomiting blood or “coffee-grounds”; B) Red or dark brown urine; C) Tarry, black, coffee-ground, or red-colored stools
Question: Which of the following describes the particles in a desirable suspension?
Answer Options:
A) The particles are crystallizing
B) The particles are caked at the bottom
C) The particles are of uniform (same) size
Answer: C) The particles are of uniform (same) size.
Question: The active ingredient for a drug formulation intended to be taken orally for a systemic effect is extremely sour and smells foul. Which dosage form would best mask the sour taste and foul smell?
Answer Options:
A) Unflavored troche
B) Uncoated tablet
C) Hard gelatin capsule
Answer: C) Hard gelatin capsule
Question: Which of the following are characteristics of qualitative research? Select all that apply
Answer Options:
A) Anonymity is often not a consideration
B) Uses the concept of saturation to determine sample size
C) Research question format indicates a correlation or relationship between the independent and dependent variables
D) Usually has a small sample size
E) Research question is framed as a hypothesis
Answer: B) Uses the concept of saturation to determine sample size; D) Usually has a small sample size
Question: Data gathered on age and assertiveness levels of registered nurses indicate a correlation coefficient of .80. This indicates
Answer Options:
A) No relationship
B) Positive relationship
C) Inverse relationship
D) Negative relationship
Answer: B) Positive relationship
Question: Generalizability in research refers to:
Answer Options:
A) The extent to which findings from an analysis are unlikely to be the result of chance
B) The extent to which research findings are reported objectively
C) The extent to which results of a study can be applied to other people
D) The extent to which statistical significance is related to clinical significance
Answer: C) The extent to which results of a study can be applied to other people
Question: In the context of ethical principles, what is beneficence?
Answer Options:
A) Participants’ right to self-determination
B) Researcher must be qualified to conduct research
C) Researchers’ obligation to protect participants’ privacy
D) Researchers’ obligation to maximize benefits and minimize harm
Answer: D) Researchers’ obligation to maximize benefits and minimize harm
Question: Respondents were asked to identify, on a seven-point scale, the degree to which they agreed or disagreed with the statement: “The nursing care I received during my hospital stay considered my needs as an individual.” This is an example of which of the following scales?
Answer Options:
A) Semantic differential scale
B) Visual analog scale
C) Sort scale
D) Likert scale
Answer: D) Likert scale
Question: The nurse researcher has identified the study problem and variables. The nurse is now writing a formal statement of the expected relationship between the variables in a specific population. What portion of the study is the researcher developing?
Answer Options:
A) Variable
B) Research question
C) Objective
D) Hypothesis
Answer: D) Hypothesis
Question: The nurse researcher is writing the operational definition of a study variable. What information should be included in this definition?
Answer Options:
A) How the variable will be measured in a study
B) How the variable is defined in the study
C) How the variable relates to the specific group to be studied
D) How the variable relates to the hypothesis
Answer: A) How the variable will be measured in a study