Question: John is allergic to sulfa antibiotics he most likely will have a cross sensitivity to?

Answer Options:
Loop diuretics
Sulfonylureas
Thiazide diuretics
All of the above

Correct Answer: 4. All of the above

Answer:

Question: Ethnic differences have been found in drug:

Answer Options:
Absorption
Hepatic metabolism
Filtration at the glomerulus
Passive tubular reabsorption

Correct Answer: 2. Hepatic metabolism

Answer:

Question: The U.S. Food and Drug Administration regulates:

Answer Options:
Prescribing of drugs by MDs and NPs
The official labeling for all prescription and over-the-counter drugs
Off-label recommendations for prescribing
Pharmaceutical educational offerings

Correct Answer: 2. The official labeling for all prescription and over-the-counter drugs

Answer:

Question: The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:

Answer Options:
Minimum adverse effect level
Peak of action
Onset of action
Therapeutic range

Correct Answer: 3. Onset of action

Answer:

Question: The time required for the amount of drug in the body to decrease by 50% is called:

Answer Options:
Steady state
Half-life
Phase II metabolism

Correct Answer: 2. Half-life

Answer:

Question: The NP instructs the patient not to crush a time release capsule. What is the primary result that could possibly lead to?

Answer Options:
Disintegration
Toxicity
Malabsorption
Deterioration

Correct Answer: 2. Toxicity

Answer:

Question: Ray has been diagnosed with hypertension and an angiotensin-converting enzyme inhibitor is determined to be needed. Prior to prescribing this drug, the NP should assess for:

Answer Options:
Hypokalemia
Impotence
Decreased renal function
Inability to concentrate

Correct Answer: 3. Decreased renal function

Answer:

Question: ACE inhibitors are the drug of choice in treating diabetic hypertension because they:

Answer Options:
Improve insulin secretion
Improve renal secretion of potassium
Reduce the production of angiotensin II
B and C

Correct Answer: B and C

Answer:

Question: When prescribing this type of calcium channel blocker, the nurse practitioner will instruct the patient on the possible adverse effects of:

Correct Answer: 1. Edema of the hands and feet

Answer:

Question: Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel blocker?

Answer Options:
Bradycardia
Hepatic impairment
Increased contractility
Edema of the hands and feet

Correct Answer: 4. Edema of the hands and feet

Answer:

Question: Harold, a 42-year-old African American, has moderate to persistent asthma. The nurse practitioner would avoid using which of the following medication?

Answer Options:
Betamethasone, an inhaled corticosteroid
Salmeterol, an inhaled long-acting beta-agonist
Albuterol, a short-acting beta-agonist
Montelukast, a leukotriene modifier

Correct Answer: 2. Salmeterol, an inhaled long-acting beta-agonist

Answer:

Question: Harold, a 42-year-old African American, has moderate persistent asthma. Which of the following asthma medications should be used cautiously, if at all?

Answer Options:
Betamethasone, an inhaled corticosteroid
Salmeterol, an inhaled long-acting beta-agonist
Albuterol, a short-acting beta-agonist
Montelukast, a leukotriene modifier

Correct Answer: 2. Salmeterol, an inhaled long-acting beta-agonist

Answer:

Question: Sam is a 72-year-old male that takes diphenhydramine for seasonal allergies. The NP would instruct the patient to monitor for which of the following:

Answer Options:
Urinary retention
Cardiac output
Peripheral edema
Skin rash

Correct Answer: 1. Urinary retention

Answer:

Question: Howard is a 72-year-old male who occasionally takes diphenhydramine for his seasonal allergies. Monitoring for this patient taking diphenhydramine would include assessing for:

Answer Options:
Urinary retention
Cardiac output
Peripheral edema
Skin rash

Correct Answer: 1. Urinary retention

Answer:

Question: The APN understands which medications should be prescribed for COPD exacerbations?

Answer Options:
Doubling of inhaled corticosteroid dose
Systemic corticosteroid burst
Continuous inhaled beta-2-agonists
Leukotriene therapy

Correct Answer: 2. Systemic corticosteroid burst

Answer:

Question: There is often cross-sensitivity and cross-resistance between penicillins and cephalosporins because:

Answer Options:
Renal excretion is similar in both classes of drugs.
When these drug classes are metabolized in the liver, they both produce resistant enzymes.
Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-producing organisms.
There is not an issue with cross-resistance between penicillins and cephalosporins.

Correct Answer: 3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-producing organisms.

Answer: